Road Map
Step 1:
First and foremost, start off by doing a “Daily Test”. This will give you an introduction to the game, 5 of the mini-games in each of the different testing areas, and also net you the First Touch trophy. This will also give you a start towards your different brain usage % trophies.

Step 2:
Go online and play each of the different online games (Card, Time & Snatch). Once you finish one of each, you will have your Card Game!, Time Game!, & Snatch Game! Trophies. You do not have to win in order to get these, just complete them. Fast way to complete a game is to select either easy (card), 30 seconds (time), or 10 quizes (snatch) as your match settings.

Step 3:
Go back to doing “Daily Tests” and keep redoing them until you until you reach 100% brain usage. This is EXTREMELY time consuming and difficult as the higher your brain usage is, the harder everything gets. If you find yourself having problems with certain mini-games, you can always practice them in the “Training Room”. Doing this will net you all 3 of the “% Brain Usage” trophies. This also unlocks the mini-games in the Training Room.

Note: There is a cheat to this that you can do and while it does help, it is still a pain in the butt. If you have a phone, camera or video recorder, you can either record or take a picture of the screen, then pause the game, figure out which button(s) you have push for the correct answer, unpause the game, select the answer and then repeat.

Step 4:
Go to training mode and play every type of mini-game there is in each of the different catagories (in both brain training & stress training). You must play each game in easy, medium & hard levels and get an A+ rating on them as well. If you are having problems with certain ones, either keep practicing or use the “cheat” mentioned above to help you get through the more difficult ones. While doing these, it’s best to try to get your Combo trophy by getting 30 answers in a row correct in one mini-game! Once all completed and you have you’re A+ in each, you will get your King Of Brain trophy.

Step 5:
This is going to be the hardest trophies yet and will mostlikely cause most people to put the game down and say forget it. Honestly, these trophies wouldn’t be that hard at all since you could easily boost your way through them, but you WILL need to find a boosting partner as there is almost no one on to play this game. You have to go online and play each of the types of games enough times to get yourself to Level 100 in each. This is not an easy task at all as most of the people at level 100 I see have about 1800-2000 game wins in EACH of the games. Also, it is extremely difficult to keep track of your progress as the leaderboards are messed up and it is extremely difficult (almost impossible) to see how many wins you are at or anything. You can kinda see your totals if you move back and forth from one category to the next fast (your number will blink for a second at the bottom of the one you just left).

Note: Easiest way I found to boost is to have 2 PS3 systems with both having the game on it. I know not everyone has 2 systems, but if you have a friend that has the game as well and you both are looking to get the trophies, maybe borrow each other's systems for a few days and knock them out. It also makes it easier since normally you won't have internet connection lag/losing game problems & don't have to plan times to meet up to play when you're both free, you can just do it on your own time. The way I do it is I just log myself into one of the PS3s and use my wife's system to log her on to hers and invite her to join my private games, then we take turns winning to boost our totals. You can obviously do this with a friend/boosting partner online, but this way you don't have to make someone sit there through 1800 wins just so you can get it.

Conclusion:
Like I said, this game is VERY hard to 100%. The game itself is very fun to play normally and is a great test of your mental abilities, but as trophy hunting goes, it will probably drive you insane by the end of it. If you keep to the path above (with 4 & 5 being switchable depending on which you prefer doing first), than you should have a slightly easier road. I would just say focus on one trophy type at a time and finish it before moving on to the next one. Take your time, and with a lot of patience and determination, you should be able to one of the VERY few that have 100%’d this game.

 

[PS3T Would Like to Thank OnceFallen for this Road Map]