I didn't get far in Fallout NV. Haven't even made it to Vegas lol!

I do remember the quest for Ed-E was glitched since I spoke to the lady at the scrapyard first so my robot was only half upgraded and he was the campanion I planned to take through the game. :/
Skyrim is similar like I found some quest items before the quest was started then the person wouldn't take the item off my hands so I end up with open quests I can't complete and items in my inventory I can't get rid off. It's annoying the hell out of me lol!