Originally Posted by ShackledDreams
Honestly, the easiest way to finish her off is with a weapon that doesn't lock on (sit still and take aim, then dodge like hell). I ended up using Reaper to take her down on Twisted. His flaming chainsaw takes out the cars in one shot, knocks her to the bridge in 5 shots and finishes off the head in 2-3 shots (if I remember correctly). You'll want to save any power missiles, mega guns and artillery ammo for the mini bridge fight (just unloading on her) as her pounding makes it impossible to lite up the chainsaw. Mega guns also work well on her in any stage (when she's sitting still).
Wottagunn and I also have tips for taking down the other two bosses in our Twisted Metal Trophy Guide
. All the tips etc there work to beat the Gold Medal times on Twisted difficulty (a few attempts pending, of course).
I see how add this if you want. I just am chilling on the other side of bridge and she doesn't fly up and down like crazy I have to redo it almost had it and I was using that town truck and death warrant, ill try reaper real quick though I am really comfortable with these two.